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Testosterone may be aromatized to estradiol in adipocytes and a negative feedback loop wherein exogenously administered testosterone results in decreased spermatogenesis via inhibition of follicle-stimulating hormone (FSH) and LH can occur

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Liraglutide affects body weight and upregulates GLP-1R in the cartilage tissues of the knee OA rat model Previous studies have indicated that liraglutide was involved in weight loss [15, 16]

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